Cycloastragenol’s core mechanism is supporting telomerase activity — the enzyme that maintains telomere length at chromosome ends. These protective structures naturally shorten with each cell division, a process directly linked to ageing. Human studies have shown notable results at a dose of 10mg/day, supporting this dosage for extended use.

This extract’s strength lies in its exceptional concentration: over 90% pure cycloastragenol, verified by HPLC analysis — radically different from standard astragalus or astragaloside IV extracts, whose absorption depends heavily on gut flora and is thus variable person to person. Highly purified cycloastragenol crosses the intestinal barrier directly, ensuring a consistent, predictable response regardless of individual microbiome status.

Astragaloside IV, often presented as astragalus’s main active, needs metabolic conversion by gut microbiota to become cycloastragenol, the form actually active on telomerase — a random, individual-dependent biotransformation step explaining the high variability seen with standard extracts. Purified cycloastragenol (>90%) bypasses this entirely by supplying the active molecule directly.

Take one 10mg capsule a day, preferably in the morning with a glass of water; avoid taking with very fatty meals to maximise absorption. Research supports 10mg/day as the best balance of efficacy and tolerance, with no significant added benefit at higher doses. A course of three to twelve months is possible depending on individual goals, with no need for a gradual dose increase.

For adults only. Not recommended for pregnant or breastfeeding women or children. Do not exceed the recommended daily dose of one capsule. If you have a chronic condition or take medication concurrently, consult a healthcare professional before use. Store in a cool, dry place away from direct light and moisture, out of reach of young children.

How exactly does cycloastragenol act on telomeres?

It actively supports telomerase, the enzyme that adds specific nucleotide sequences to chromosome ends, helping maintain telomere length.

Who is this product mainly for?

Mainly adults wanting to support cellular ageing prevention or immune system performance — particularly those over 40, or people exposed to significant oxidative stress from pollution or an intensive lifestyle.

How do I choose among different astragalus extracts?

For real telomere-supporting effect, prioritise cycloastragenol purified above 90%, HPLC-verified, rather than astragaloside IV or whole-root extract — purity and manufacturing rigour directly determine telomerase-supporting action.

Herba Barona is an independent specialist supplement shop in the heart of Paris — established in 2006. What you order is genuinely on our shelves: we ship from our own stock, with no dropshipping and no long waits.

Visit us at 10 rue Théophile Roussel, Paris 12 — or use Click & Collect and pick up your order in-store. We also deliver across France and Europe. Friendly, expert advice in English from our team.

Where is the shop?

Herba Barona is at 10 rue Théophile Roussel, 75012 Paris — a two-minute walk from Ledru-Rollin (line 8), close to Bastille. Open Tuesday to Saturday, 9:30 am–6:30 pm.

Can I order online or collect in store?

Yes. We ship across France and Europe under the same conditions as our French store, or choose Click & Collect to pick up your order for free at our Paris shop.