Griffonia simplicifolia is an African climbing plant whose seeds naturally contain 5-HTP (5-hydroxytryptophan), an amino acid rare in the plant kingdom. 5-HTP is the direct precursor of serotonin, an essential neurotransmitter often called the “happiness molecule.” Once ingested, 5-HTP crosses the blood-brain barrier and is converted into serotonin, which regulates mood, sleep, appetite and stress. In the evening, serotonin is converted into melatonin, the sleep hormone — explaining Griffonia’s dual interest for both mood AND sleep. Each capsule contains 500 mg of griffonia seed extract standardised to 15% 5-HTP, i.e. 75 mg of pure 5-HTP, matching the dosage used in clinical study protocols.

Griffonia 5-HTP acts on three complementary fronts. Mood and emotional wellbeing: by maintaining adequate serotonin levels, it supports emotional balance during low-mood periods, overwork or seasonal change — one of the most requested anti-stress supplements in our Paris shop. Sleep: by supporting the serotonin-to-melatonin conversion, it helps with falling asleep and sleep quality; taken in the evening, 30 minutes before bed, it naturally prepares the body for rest. Appetite regulation: serotonin plays a central role in satiety, and adequate levels reduce compulsive snacking urges, especially sugar cravings later in the day — making Griffonia a useful ally for weight management too.

For mood: 1 capsule in the morning with breakfast. For sleep: 1 capsule in the evening, 30 minutes before bed. Dose: 1 to 2 capsules a day maximum (75–150 mg of 5-HTP). Suggested course: 2 to 3 months, followed by a break of a few weeks. The 100-capsule bottle covers 50 days at 2 capsules/day, or over 3 months at 1 capsule/day. It pairs well with magnesium (a cofactor in the conversion of 5-HTP to serotonin), ashwagandha (which regulates cortisol via a complementary pathway) or L-theanine (for calm, attentive focus during the day).

Do NOT combine Griffonia 5-HTP with antidepressants (SSRIs, SNRIs, tricyclics, MAOIs) without medical advice — risk of serotonin syndrome. Not recommended for pregnant or breastfeeding women. Stop 2 weeks before scheduled surgery. Do not combine with direct melatonin supplementation without professional advice. This food supplement is not a substitute for a varied, balanced diet and a healthy lifestyle. Do not exceed the recommended daily dose. Keep out of reach of children.

How long before Griffonia takes effect?

Sleep effects can be felt within the first few days. Mood effects generally appear after 2–3 weeks of regular use. A 2–3 month course is recommended for lasting results.

What’s the difference between Griffonia and Tryptophan?

Tryptophan must be converted into 5-HTP and then serotonin (2 steps). Griffonia provides 5-HTP directly, with only one conversion step to serotonin — making it more direct and efficient at an equal dose. Do not combine the two without medical advice.

Can Griffonia be taken with antidepressants?

No, except with explicit medical advice — 5-HTP increases serotonin, and SSRI antidepressants prevent its reuptake, so combining them could cause serotonin syndrome. Always consult your doctor.

Is Griffonia vegan?

Yes, the extract is 100% plant-based (griffonia seeds) and the capsule is HPMC. No additives, colourings or preservatives.

Herba Barona is an independent specialist supplement shop in the heart of Paris — established in 2006. What you order is genuinely on our shelves: we ship from our own stock, with no dropshipping and no long waits.

Visit us at 10 rue Théophile Roussel, Paris 12 — or use Click & Collect and pick up your order in-store. We also deliver across France and Europe. Friendly, expert advice in English from our team.

Where is the shop?

Herba Barona is at 10 rue Théophile Roussel, 75012 Paris — a two-minute walk from Ledru-Rollin (line 8), close to Bastille. Open Tuesday to Saturday, 9:30 am–6:30 pm.

Can I order online or collect in store?

Yes. We ship across France and Europe under the same conditions as our French store, or choose Click & Collect to pick up your order for free at our Paris shop.