Pycnogenol is a patented extract from maritime pine (Pinus pinaster) bark, trademarked by Swiss laboratory Horphag Research, which holds the exclusive extraction process. It’s distinguished by an exceptional concentration of small, highly bioavailable procyanidins (OPC), strictly standardised to at least 70% — a consistency that has made it one of the most studied botanical actives in the world, with over 160 clinical publications.

Pycnogenol’s OPCs exert strong antioxidant activity, neutralising free radicals responsible for oxidative stress. Beyond that cellular protection, it’s particularly studied for its effect on blood microcirculation and leg comfort: procyanidins help support vascular wall flexibility and normal venous return, making it a useful ally during hot weather or long periods standing. It’s also studied for its role in supporting cognitive function via cerebral microcirculation.

Take 1 capsule a day with water, ideally with a meal to aid polyphenol absorption. The 100mg dose suits those seeking stronger microcirculation support or sustained antioxidant action; a 50mg version is available for maintenance use.

Sourced directly from Horphag Research to guarantee authenticity, and packed in France in HACCP-certified facilities. Each batch is independently tested for OPC content, contaminants and microbiological compliance.

Not recommended for pregnant or breastfeeding women without prior medical advice. People on anticoagulant or antiplatelet medication should consult a healthcare professional before use, due to OPCs’ effect on microcirculation. Store in a dry place away from light and heat, out of young children’s reach.

Who is this 100mg dose for?

Adults wanting strong antioxidant support and a targeted effect on microcirculation — including those prone to heavy legs, people who stand for long periods, seniors focused on cognitive health, and athletes in recovery.

Can it be combined with other antioxidants?

Yes — with vitamin C or zinc for broader antioxidant support. Avoid stacking several highly concentrated OPC sources at once; alternating with grape seed extract over several months is a common approach.

How does Pycnogenol differ from a generic pine bark extract?

Pycnogenol is patented, produced by Horphag Research’s exclusive water-based extraction process, and standardised to at least 70% OPC with over 160 clinical trials behind it — a level of consistency and validation generic extracts don’t offer.

Herba Barona is an independent specialist supplement shop in the heart of Paris — established in 2006. What you order is genuinely on our shelves: we ship from our own stock, with no dropshipping and no long waits.

Visit us at 10 rue Théophile Roussel, Paris 12 — or use Click & Collect and pick up your order in-store. We also deliver across France and Europe. Friendly, expert advice in English from our team.

Where is the shop?

Herba Barona is at 10 rue Théophile Roussel, 75012 Paris — a two-minute walk from Ledru-Rollin (line 8), close to Bastille. Open Tuesday to Saturday, 9:30 am–6:30 pm.

Can I order online or collect in store?

Yes. We ship across France and Europe under the same conditions as our French store, or choose Click & Collect to pick up your order for free at our Paris shop.